This refers to a process involving the administration of estradiol (E2) to prepare the endometrium for embryo implantation. It is a component of hormone replacement therapy cycles, frequently used in frozen embryo transfers or in cases where the ovaries are not functioning optimally. This preparation aims to create a receptive uterine lining, crucial for successful implantation and pregnancy.
The use of this hormonal preparation technique is vital for individuals undergoing assisted reproductive technologies, as it can improve the chances of pregnancy by optimizing the uterine environment. Historically, various protocols have been developed to achieve optimal endometrial receptivity, and estrogen priming represents a significant approach in this area. By providing the necessary hormonal support, this method addresses potential deficiencies and aims to mimic the natural hormonal cycle.