Direct intravenous administration of certain medications at a rapid rate, often referred to as IV push, poses significant risks. This method bypasses many of the body’s natural defenses and buffering systems, potentially leading to severe adverse reactions. An example includes potassium chloride, which, if administered rapidly, can induce life-threatening cardiac arrhythmias.
Understanding which pharmaceuticals are unsuitable for rapid intravenous injection is crucial for patient safety. This knowledge base helps prevent immediate toxicity, tissue damage from extravasation, and unintended hemodynamic consequences. The recognition of high-risk drugs has evolved over time with increased pharmacological research and clinical experience, leading to more stringent guidelines for medication administration.