The subjective experience during Spravato administration varies between individuals. Common sensations reported include feelings of dissociation, altered perceptions of reality, changes in sensory experiences (visual and auditory), and a sense of unreality. Some individuals also report experiencing mild euphoria or calmness, while others may encounter anxiety or mild confusion. These effects are generally transient, typically resolving within one to two hours following administration. The intensity and nature of these sensations are influenced by dosage, individual physiology, and the overall clinical context.
Understanding the potential sensations associated with this treatment is crucial for patient preparation and management. A comprehensive understanding helps mitigate anxiety and promotes a collaborative approach to care. The emergence of such treatment options represents a significant advance in the therapeutic landscape for treatment-resistant depression, offering hope to individuals who have not responded to traditional antidepressant medications. The treatment protocol, including the monitoring period, is designed to ensure patient safety and to address any adverse reactions promptly.