The term designates a specific type of fatty deposit that accumulates within the walls of arteries. This buildup, composed primarily of cholesterol, cellular waste products, and calcium, leads to the hardening and narrowing of the affected blood vessels. An example includes the formation of plaque in the coronary arteries, potentially leading to diminished blood flow to the heart muscle.
Its significance resides in its direct link to cardiovascular diseases, including heart attacks, strokes, and peripheral artery disease. Early identification and management are crucial to mitigate the risks associated with this arterial condition. Historically, its understanding has evolved significantly, influencing the development of preventative measures and treatment strategies aimed at reducing its prevalence and impact on public health.
