Certain substances can disrupt or impede accurate measurement in analytical procedures. These substances compromise the integrity of results by interacting with reagents, instruments, or target analytes in unforeseen ways. Consideration must be given to their identification and mitigation to ensure the reliability of laboratory findings.
The impact of these disruptive substances can be profound across a spectrum of scientific disciplines, affecting clinical diagnoses, environmental monitoring, and quality control processes. Historically, understanding and controlling for these factors has been pivotal in advancing scientific rigor and reproducibility, leading to more accurate interpretations and evidence-based decisions. Rigorous method development and quality control procedures are crucial for minimizing their impact.